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Epacadostat  ≥98%（HPLC）

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包装规格：5mg 25mg 100mg in glass bottle
产品简介：一种口服的IDO1抑制剂，具有潜在的免疫调节和抗肿瘤活性。 Epacadostat is an orally available hydroxyamidine and inhibitor of indoleamine 2,3-dioxygenase (IDO1), with potential immunomodulating and antineoplastic activities. INCB024360 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine. By inhibiting IDO1 and decreasing kynurenine in tumor cells, INCB024360 increases and restores the proliferation and activation of various immune cells, including dendritic cells (DCs), NK cells, and T-lymphocytes, as well as interferon (IFN) production, and a reduction in tumor-associated regulatory T cells (Tregs)。
溶解性：溶于DMSO（200mg/ml）
保存条件：-20℃

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