ISX9  ≥98%(HPLC)

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包装规格:5mg 25mg 100mg in glass bottle
溶解性:溶于DMSO(≥37mg/mL)
产品描述:一种神经源性药物,促进体内神经发生,促进海马亚颗粒区(SGZ)神经母细胞的增殖和分化,促进成年齿状回神经元的树突状树突形成。 ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proliferation and differentiation of hippocampal subgranular zone (SGZ) neuroblasts, and the dendritic arborization of adult-generated dentate gyrus neurons. Isx-9 also improves hippocampal function, enhancing memory in the Morris water maze. Notably, Isx-9 enhances neurogenesis and memory without detectable increases in cellular or animal activity or vascularization. Isx-9 enhances hippocampal neurogenesis and memory in vivo, and its effects are reliant on Mef2, revealing a novel cell-intrinsic molecular pathway regulating adult neurogenesis。
保存条件:-20℃