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Pevonedistat 促销  99.2157%

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包装规格：1mg 5mg 25mg in glass bottle
溶解性：溶于DMSO(10mg/mL)
产品描述：一种NAE（NEDD8激活酶)抑制剂，IC50:4nM，具有潜在的抗肿瘤活性。 Pevonedistat is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 binds to and inhibits NAE, which may result in the inhibition of tumor cell proliferation and survival. NAE activates Nedd8 (Neural precursor cell expressed, developmentally down-regulated 8), an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP)。
保存条件：-20℃

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