生物试剂
>
生化试剂
>
信号通路
> (±)-他齐茶碱
加入收藏 取消收藏

(±)-他齐茶碱  ≥98%

促销价¥{{model.attbuying.price}}

市场价¥0.00

累计销量0 累计评价0 人评论

别称 {{model.alias}}
中文名称 {{model.name}}
英文名称 {{model.enname}}
品牌 {{model.brand}}
CAS {{model.cas}}
分子式
分子量 {{model.molecularweight}}
MDL {{model.mdl}}
货号 {{model.procode}}
数量

+ -

件 库存{{model.attbuying.number}}件
立即购买 加入购物车 下载说明书

看了又看
包装规格：1mg 5mg 10mg 25mg 50mg 100mg in glass bottle
产品描述：基本信息 产品编号： T11451  产品名称： (±)-Tazifylline CAS: 79712-55-3   储存条件 粉末 -20℃ 四年 分子式： C23H32N6O3S 溶于液体 -80℃ 二年 分子量 472.60     化学名：  7-[2-hydroxy-3-[4-(3-phenylsulfanylpropyl)piperazin-1-yl]propyl]-1,3-dimethylpurine-2,6-dione Solubility (25°C)：   体外:   DMSO   Ethanol   Water   体内(现配现用):   ＜1mg/ml表示微溶或不溶。 普西唐提供的所有化合物浓度为内部测试所得，实际溶液度可能与公布值有所偏差，属于正常的批间细微差异现象。 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。   生物活性 产品描述 一种有效的，选择性的长效组胺 H1 受体拮抗剂。 靶点 H1-receptor   体外研究 Tazifylline potently inhibits contractions evoked by stimulation of histamine H1-receptors in isolated guinea pig ilea and exhibits high affinity for these receptors in radioligand binding studies in vitro Tazifylline has much lower affinity for histamine H2-receptors,alpha- and beta-adrenoceptors,5-hydroxytryptamine and muscarinic receptor subtypes.Tazifylline poorly inhibits the release of histamine from rat peritoneal mast cells. 体内研究 In rats,guinea pigs and dogs the antihistaminic effect of Tazifylline is rapid in onset and long-lived.In anesthetized guinea pigs,Tazifylline markedly inhibits histamine-induced bronchoconstriction and protects conscious animals from the lethal effect of large doses of the amine.In conscious rats,Tazifylline is more potent in reducing the inflammatory effects of intradermal histamine than that evoked by anaphylactic reaction.In conscious dogs,orally administered Tazifylline inhibits histamine-induced skin inflammation for long periods of time and in anesthetized animals attenuated that portion of the histamine-evoked hypotension attributable to stimulation of H1-receptors.Large oral doses of Tazifylline does not reduce spontaneous locomotor activity in mice,nor do they produce overt symptoms of behavioral depression in conscious rats.
保存条件：-20℃

猜你喜欢