特立氟胺 促销  ≥98%(HPLC)

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包装规格:50mg 100mg 1g in glass bottle
产品简介:一种来氟米特的活性代谢产物,它抑制嘧啶合成,因此有效降低T细胞和B细胞增殖。 Teriflunomide is the active metabolite of leflunomide. Teriflunomide is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It is uncertain whether this explains its effect on MS lesions. Teriflunomide inhibits rapidly dividing cells, including activated T cells, which are thought to drive the disease process in MS. It has been found that teriflunomide blocks the transcription factor NF-κB.
溶解性:溶于DMSO(5 mg/mL 加热)
保存条件:-20℃