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GSK461364A  ≥98%(HPLC)

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包装规格：5mg 25mg 50mg 100mg in glass bottle
溶解性：溶于DMSO(100mg/mL)。
产品描述：一种PLK1抑制剂，Ki：2.2nM。GSK-461364 is a Polo-like kinase 1 inhibitor, is also a small molecule Polo-like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo-like kinase 1 inhibitor GSK461364 selectively inhibits Plk1, inducing selective G2/M arrest followed by apoptosis in a variety of tumor cells while causing reversible cell arrest at the G1 and G2 stage without apoptosis in normal cells. Plk1, named after the polo gene of Drosophila melanogaster, is a serine/threonine protein kinase involved in regulating mitotic spindle function in a non-ATP competitive manner.
保存条件：-20℃

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